Word: tumors
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...stickiness in more commonplace ailments, including cancer. "Cellular-adhesion research isn't going to cure cancer, but it might stop metastasis," says Massachusetts Institute of Technology scientist Richard Hynes. At the La Jolla Cancer Research Foundation in California, genetic scientists have succeeded in inserting a CAM gene inside a tumor cell. Once the cell starts manufacturing patches of biological Velcro, it is essentially "glued in place. It becomes incapable of metastasizing," says Erkki Ruoslahti, president of the foundation. A second approach to controlling cancer is known as "walking on ice." Here the goal is to deny tumor cells traction...
...vice president of the National Right to Life Committee, voiced his opposition at a White House photo opportunity several months ago. "If that plan was in effect when I was born in Texas," Powell told the President, "I'd be dead today." As an infant, Powell developed an inoperable tumor that attacked his spinal cord and left him paralyzed from the waist down. Though the case seemed terminal, he was saved by an innovative doctor. Oregon Medicaid director Jean Thorne disputes Powell's charge. His condition would have been covered, she says, provided a physician could be found who considered...
...REASON THAT BRAIN CANCER IS SO TERRIFYING is that tumors tend to bury themselves deep in the gray matter, where scalpels and lasers cannot reach them without doing irreparable damage to the patient's mind. That is why scientists were particularly excited by an ingenious experiment reported last week in Science magazine. The procedure is a form of gene therapy, but it turns conventional molecular engineering on its head. Rather than trying to inject good genes into cells that lack their beneficial properties, scientists have found a way to put bull's-eyes on tumor cells in order to shoot...
Eventually, using DNA probing techniques on 31 pediatric tumor samples, Garcea showed that a large fraction of the samples reacted with the sequence for the SV40 t-antigen...
...designed to overcome the basic limitation faced by all conventional cancer therapies: in doses sufficient to do their job, they can destroy the bone marrow, the mother lode of all blood cells, red and white. By removing a portion of the bone marrow (and purging it separately of tumor cells), physicians can go on to deliver otherwise lethal doses of radiation and chemotherapy. Then they rescue the patient from certain death with a reinfusion of the undamaged marrow...