Word: tumors
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...also contending with malignancies that have spread and are no longer curable. Many Americans were stunned to hear that the Edwardses will continue their quest for the White House, with Elizabeth campaigning despite metastatic breast cancer. Snow, who was treated for colon cancer two years ago and now has tumor cells on his liver, will take time off but expects to return to his post...
...breast, colon, prostate and even lung. The gains include an explosion of new drugs that are more targeted and less toxic than old-school chemotherapeutic agents. In addition, new tests are beginning to help doctors match drugs more precisely to the genetic and molecular makeup of an individual tumor. Finally, there are remarkable advances in managing the side effects of treatment, which, in the past, could be as debilitating as cancer itself...
...cancer therapies. While older drugs were like heavy artillery - obliterating cancer cells but causing lots of collateral damage - newer drugs are more like smart bombs. Some of them target communication signals within malignant cells, some cut off supply lines by interfering with the growth of blood vessels around a tumor, and others block the chemical agents that enable tumors to expand into new territory. These more targeted therapies tend to focus on frantically proliferating cancer cells while leaving healthy cells intact...
...today than ever. Until 10 years ago, there was only one drug, a chemotherapy agent, available to treat colon cancer, and it wasn't very effective. In the past decade, more chemotherapy drugs, which are easier on the body, and new classes of targeted therapies, which specifically block a tumor's ability to recruit growth factors and blood vessels, have improved the survival of patients...
...containing colon cancer in people like Snow is the ability to detect recurrent tumors. Current imaging tests including MRI and PET scans may not pick up the small micrometastases that seed repeat growths; PET scans rely on the tumor's voracious appetite for glucose for energy, but until the tumor's activity reaches a certain threshold, it won't show up on the scan. So researchers are working on finding protein markers in the blood released by tumor cells that spread outside the colon; experts believe that cancer cells that venture outside the original tumor are equipped with special markers...