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TOMMY OUT OF TUNE? During his years as head of Sony Music, Tommy Mottola had some relationships sour in very public ways. After launching the career of Mariah Carey, he married her; after a bitter divorce, she left the label. And when Michael Jackson decided that the label hadn't publicized his album enough, he drove a bus around Manhattan holding a poster of Mottola with horns. Now Mottola is facing another breakup. He announced last week that he wanted to start his own label and was leaving Sony, where since 1989 he has guided singers like Jennifer Lopez. Whether...
...HORIZON Researchers are exploring two related molecules, gaba and glutamate, that are responsible for 90% of chemical signaling in the brain. Because they control so much of the brain's activity, the trick is to fine-tune their levels in ways that relieve depression but don't affect other brain functions. Other targets of drug development: the sex hormone testosterone (a transdermal patch proved effective in a recent clinical trial for men); the stress hormone cortisol, which researchers are trying to regulate with the abortion drug RU 486 and compounds called CRF antagonists; the dynorphins (the evil twins of feel...
...Tune in to ABC World News Tonight, on Monday, Jan. 13, at 6:30 p.m. E.T., for a related story on the link between depression and osteoporosis
...know that every product has been personally chosen and tested by Alain Ducasse," explains Agnès Defontaine, who was responsible for putting Ducasse's concept in place. But the store's true raison d'être is elsewhere. "Be offers a new way of eating that's in tune with the times, that fits into our schedule while fulfilling our fancies," says Ducasse. That is, fast food. In Be's ultra-modern basement kitchen, eight young cooks are hard at work making snacks the French can be proud of. The shop's glass-fronted counter is stocked with...
...triumph, from World War II sailors capsized in shark-infested waters to families made homeless by tornadoes. (If there isn't a storm on the radar, there's always one in the video vault.) Half an hour in length, the show is meant to extend the average viewer tune-in of 12 minutes. "If the same people watch 10% longer," says Burke, "it's the same as growing your ratings...