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...year-olds.") Even David Moldawer, the associate editor who helped sign Hutchins to St. Martin's dismisses novel podcasting's growth. "It's a very small community," Moldawer, who now works for Penguin Books, told TIME. "I think the podcasting thing in general has definitely flattened out." Audio-type books require a longer commitment than reading a book, he adds, and sifting the wheat from the chaff is a time-consuming process...
These troubles are not new. The National Transportation Safety Board first investigated the medical-helicopter industry's crash epidemic in 1988. It found that low visibility, often caused by bad weather, accounted for 61% of all crashes. "Weather-related accidents are the most common and the most serious type of accident experienced by EMS helicopters," the report found, "and are also the most easily prevented...
Before that can happen, however, Melton wants to learn more about how diseases develop. And iPS cells make that possible too. For the very first time, he can watch Type 1 diabetes unfold in a petri dish as a patient's cells develop from their embryonic state into mature pancreatic cells. The same will be true for other diseases as well. "There is a good reason we don't have treatments for diseases like Parkinson's," says Melton. "That's because the only way science can study them is to wait until a patient appears in the office with symptoms...
...true power of reprogramming, however, does not stop with the stem cell. This summer, Melton flirted with the rules of biology once again when he generated another batch of history-making cells, switching one type of adult pancreatic cell, which does not produce insulin, to a type that does - without using stem cells at all. Why, he thought, do we need to erase a mature cell's entire genetic memory? If it's possible to reprogram cells back to the embryo, wouldn't it be more efficient in some cases to go back only part of the way and simply...
...August Melton bypasses stem cells altogether and transforms a type of mouse pancreatic cell that does not produce insulin into one that does...