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...future approaches won't stop with drug treatments. Petersen notes that researchers are also forging ahead with innovative screening tests to identify Alzheimer's patients sooner - before too much deterioration occurs in the brain. Better screens could also potentially identify patients by the specific type of brain buildup - plaques vs. tangles - that is causing them the most severe problems. That kind of triage early on could help doctors target the right patients with the most effective therapies...
...showed that the introduction of four genes into an adult human skin cell could reprogram it back to an embryonic state (Yamanaka had reported the same achievement in mice the previous year). Like embryonic stem cells, these reprogrammed adult cells could be coaxed into becoming any other type of cell - from skin to nerve to muscle. But researchers questioned whether the new stem cells would behave as predictably or as safely as embryonic stem cells, or whether iPS would consistently yield usable cells. "Our work shows that the original method developed by Yamanaka works great," says Eggan...
...remain ambivalent about how to feel about the suicidal man himself - the only one, after all, to be physically harmed in the affair. It's surprising how many people have counseled me to reserve sympathy. He may have been a criminal or murderer, they say, a Crime and Punishment type, driven by shame or distraction to impose self-justice and end his guilt. In the ongoing discussion in my head, however, I counter with an equally plausible circumstance: a young poet, troubled by the world, driven by shame or distraction to oblivion on the tracks...
...hearing loss. We've conducted studies of a few MP3 players and found very similar results across the MP3 manufacturers. Some in-the-ear earphones are capable of providing higher sound levels than some over-the-ear earphones. That said, studies we've done on behavior show that the type of earphones has almost nothing to do with the level at which people set their headphones. It's all dictated by the level of background noise in their listening environment. When we put people in different listening environments, like flying in an airplane - we used noise we'd recorded while...
...week on average, most were still clinically overweight (though much less so than before). But what Jakicic and other obesity researchers stress is that a 10% reduction in body weight represents a tremendous boon for overall well-being, lowering blood pressure, improving heart health and reducing the risk of Type 2 diabetes. For the obese, the end goal should not be thinness, but health and self-acceptance, which are more realistic and beneficial objectives. "The women's health was absolutely improved," Jakicic says...