Word: typing
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Dates: during 2000-2009
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...HSCI co-director Douglas A. Melton is the first to report successful "direct reprogramming," a technique that—as its name suggests—directly transforms one type of a fully formed adult cell into another...
...Using this technique, Melton and his colleagues were able to turn ordinary mouse exocrine cells of the pancreas into beta cells, vital insulin-producing cells that die off in Type I diabetes patients...
...Daley said that his colleague's findings, which were funded by HSCI and the Maryland-based Howard Hughes Medical Institute are "really the first conclusive evidence" for reprogramming one tissue type into another...
...contrast, the new method holds the promise of going directly from one mature cell type to another. It's like a scientist becoming a lawyer without having to go back to kindergarten and grow up again, Melton says...
...Melton, who began his diabetes research in 1993 when his infant son was diagnosed with the illness, said he's obsessed with trying to find a new treatment or cure for Type 1 diabetes, in which beta cells are destroyed...