Word: urea
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Dates: during 1940-1949
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...Urea...
Proving there's nothing new under the sun is TIME'S reference (Dec. 30) to experiments of Dr. Robert Marshall Stephan with urea to combat tooth decay. Gaius Valerius Catullus, about 2,000 years ago, wrote: (Ad Egnatius, Canto XXXIX) ". . .We know the Spanish custom, how Spaniards clean their teeth and scour their gums with the same water that issues from their bladders. ... If your teeth are clean, we know how you have used your urine...
...Fortunately for moderns, Dr. Stephan's urea crystals-not yet exhaustively tested-are made synthetically, have no unpleasant taste...
Like sweat and urine, saliva contains urea, a nitrogen compound. Dr. Stephan found that two groups of antagonistic bacteria flourish in saliva: 1) the destructive lactobacilli; 2) harmless germs of the staphylococcus family. By brewing an enzyme called urease. the staphylococci split up urea in the saliva into an ammonium compound, which neutralizes the erosive acid. Dr. Stephan's conclusion: teeth may decay when the saliva does not contain enough urea, or when the staphylococci are sluggish...
...hunch that a way to save teeth from decay might be to encourage the staphylococci by giving them an extra amount of urea to work on. So he made up a mouthwash of carbamide (synthetic urea crystals). The crystals are colorless and odorless, taste cool and salty. He gave the mouthwash to 100 patients to use on their toothbrushes, found that an increased amount of calcium was deposited on their teeth...