Word: vaccinee
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That may be true, but Ho, who has been working to develop an HIV vaccine of his own, now believes that a traditional shot, one that relies on snippets of a virus to both awaken and prod the immune system to churn out antibodies, may not be the best way...
Vaccines in Vain But while AIDS scientists began making inroads in developing drug therapies, designing a vaccine was proving nearly impossible. Despite all that they have learned about HIV, experts are still missing one essential ingredient: to this day, they do not know exactly what cells or immune responses could...
Without an answer, developing vaccines is a very halting process. "The virus is a moving target," says Dr. Gary Nabel, director of the Vaccine Research Center at the National Institutes of Health (NIH). "It is constantly changing its genetic makeup through mutations. It's also a moving target because the...
It didn't take long before these futile efforts began to wear on the researchers in the field, not least of all those at ADARC, where Ho's group was attempting to develop its own vaccine - with little success. The center - which had earned such laurels for its ARV triumph...
ADARC had plenty of company. Vaccine efforts were progressing elsewhere in the AIDS community, but unevenly. Testing for one candidate, made by Merck, began in 2004 with much fanfare and ended three years later with disappointing results: not only had the vaccine not offered protection against HIV infection, but it...