Word: vaccinees
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Dates: during 1950-1959
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¶When P.H.S. licensed six firms to manufacture vaccine last April, both P.H.S. and the vaccine's developer. Dr. Jonas E. Salk, urged that manufacturers be required to show that they could produce safe vaccine consistently, in batch after batch. But this requirement was neither defined by P.H.S. nor...
¶Even when manufacturers used every precaution known, the process of making a potentially deadly virus into a safe vaccine proved unexpectedly tricky. When three separate strains of virus, all officially dead by available tests, were pooled to make the final polyvalent vaccine, the mixture sometimes showed live virus. And...
Straight-Line Theory. How could all this be? The 1,000-odd doctors who sat in on the polio symposium learned something of this from Dr. Salk himself. They had gone there, full of admiration and curiosity, to hear him and see him get a $10,000 award* for his...
Dr. Salk re-examined his straight-line theory of how the virus is inactivated to make vaccine. According to this, he can start with a virus brew so potent that there are 4,000,000 virus particles in every teaspoonful. But after 1½ days in formaldehyde there should only...
Weakening Strain. This sort of thing apparently had not happened in Dr. Salk's own labs. But if it could happen anywhere, it raised a fundamental question: should any strain of virus that is likely to cause paralysis be used in the vaccine? Dr. Salk had long contended that...