Word: vaccinees
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Dates: during 2000-2009
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Chiron's incompletely recovered operations contributed to a fifth consecutive year of initial vaccine shortages this flu season. But its largest shareholder, Swiss drug firm Novartis, did not dump its stake in the company. Quite the opposite. Novartis CEO Daniel Vasella decided to buy for $5.1 billion the 58% of...
Yet vaccines have lately begun to look more promising. Wood Mackenzie expects the market to grow from $9 billion in 2004 to $13 billion by 2009. Why? Ironically enough, Chiron's 2004 snafu had a bracing effect on Capitol Hill. Beset by fears of a possible bird-flu pandemic, Congress...
Although Chiron has won a $62.5 million government contract to develop a vaccine against the currently dreaded H5N1 bird flu, which has killed scores of people in Asia, Vasella says the pandemic scare isn't what drove his decision to buy the firm. He points out that there's still...
One way to speed things up is to toss out the eggs and grow the viruses in human cells. Any virus that can infect humans will, by definition, grow easily in human-cell cultures, so that step could cut the incubation time to three months. Chiron, one of the world...
But all these methods are just stopgap solutions, since a full-fledged flu pandemic would kill millions of people before the vats made enough vaccine to meet demand. Ultimately, vaccine makers may need to go straight to the source: the flu virus' genetic code. By extracting snippets of viral RNA...