Word: vaccinees
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Dates: during 2000-2009
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Nonetheless, many AIDS experts applauded the findings as a crucial starting point for further research. Some say that as slight as it was, the vaccine benefit discovered in the trial may eventually help scientists develop a workable AIDS vaccine - a goal that has eluded them for more than two decades...
Overall, the study found that the two-vaccine approach was 31% effective in preventing HIV infection: 51 of the roughly 8,200 people who had been inoculated eventually acquired HIV, compared with 74 people in the placebo group. The analysis that resulted in the 31% figure, however, included study participants...
Perhaps, but the release of the trial's full data has not quelled the early criticism that bubbled up around it. Some researchers contend that the second and third analyses of the data - including the "per protocol" analysis, which included only the 12,450 volunteers who received all six vaccine...
Still, after more than 25 years of virtually futile AIDS-vaccine research, the investigators involved in the Thai trial believe that their findings, while admittedly "modest," offer unprecedented leads to follow. "To quote from our recent history, this is a 'Yes we can' moment," Michael says. "It is not a...
Alan Bernstein, executive director of the Global HIV Vaccine Enterprise, suggests that the debate over which analysis of the data matters most - as well as the rather clumsy manner in which the study was presented to the public - is secondary to what the research brings to the battle against HIV...