Word: vaccinees
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Sickness and death from vaccine-preventable diseases has fallen to an all-time low in the U.S., according to researchers at the Centers for Disease Control and Prevention. Last year, there were no reported deaths in the U.S. from measles, diphtheria, mumps, polio, or rubella (German measles), according to research...
For more than a quarter-century, the medical community has been trying to develop a vaccine against AIDS--and for more than a quarter-century, it has been disappointed. Earlier this year, it seemed that science had its best shot yet, with a large trial of a new vaccine that...
The Merck vaccine used a different approach, called cell-mediated immunity. Scientists inserted three HIV genes into an ordinary cold virus and injected it into the body. Immune-system dendritic cells would, it was hoped, gobble up the virus and then display its gene markers--along with those of the...
What should have happened, however, didn't, and the vaccine provided no real protection. "I don't think anyone imagined the results would be so definitively negative," says Dr. Gary Nabel, director of the Vaccine Research Center at the National Institutes of Health.
A possible solution would be to stick with the cold virus but use different HIV genes and two injections spaced a few months apart. Dr. David Ho, director of the Aaron Diamond AIDS Research Center in New York City, thinks the answer might be to abandon the cold virus and...