Word: vaccinees
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More than 13 million people around the world have been infected with HIV, a virus which causes AIDS, and the number is expected to grow to 30 to 40 million by the year 2000, according to U.S. government estimates. But while researchers isolated HIV a decade ago, an AIDS vaccine...
One obstacle to creating a vaccine against the virus, says Dr. Martin S. Hirsch, a professor of medicine at the Medical School and director of AIDS research at Massachusetts General Hospital (MGH), is the rapid rate at which the virus mutates. "A single vaccine won't be effective against all...
Because of the uniqueness of the virus, syas Hirsch, researchers are forced to use two distinct strategies to create a vaccine. The first approach is the classical one, the strategy used for polio, mumps and measles (please see main story).
MGH researchers are pursuing a different strategy, using vaccines to stimulate the immune response of patients already sick with AIDS. Following a similar track is MicroGeneSys, a Connecticut biotechnology firm. The company initially secured $20 million in government funding for clinical trials of its vaccine GP-160, modeled on a...
-- Flu shots really are worth the fuss and bother. A three-year study of people ages 45 and older who live in the Canadian province of Manitoba found that without the vaccine, the number of hospital admissions for influenza and pneumonia would have been 40% higher.