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To overcome this obstacle, the NIH researchers-Drs. Brian Murphy, Elias Chalhub and Robert Chanock and Biologist Sandra Nusinoff-decided to beat the virus at its own flexible game. Vaccines now in use are made with a type of virus that has been killed and therefore has only limited ability...

Author: /time Magazine | Title: Medicine: Fighting the Flexible Flu | 8/21/1972 | See Source »

The virus used in the vaccine is a hybrid. Working in the NIH laboratories, the research team combined Hong Kong flu viruses from the 1968 epidemic with chemically altered samples of a 1965 strain. The result is a virus strong enough to produce immunity to the flu, but too weak...

Author: /time Magazine | Title: Medicine: Fighting the Flexible Flu | 8/21/1972 | See Source »

The new vaccine base is extremely sensitive to heat and fails to function if exposed to the high (98.6° F.) temperature of the lungs, the place where flu viruses settle to bring on illness. Otherwise a live virus could not be used. But it thrives in the slightly lower...

Author: /time Magazine | Title: Medicine: Fighting the Flexible Flu | 8/21/1972 | See Source »

District of Columbia reformatory, the vaccine, which is administered by nasal spray rather than injection, proved highly effective. Seventeen of 28 prisoners not given the vaccine came down with the flu after intentional exposure. All 17 others who were vaccinated remained free of the ailment. Nor did the men suffer...

Author: /time Magazine | Title: Medicine: Fighting the Flexible Flu | 8/21/1972 | See Source »

NIH officials warned that extensive trials and testing must still be conducted before the new vaccine can be licensed and made available to the public. But they are cautiously confident that the vaccine will be ready in time for the next predicted flu epidemic.

Author: /time Magazine | Title: Medicine: Fighting the Flexible Flu | 8/21/1972 | See Source »

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