Word: vaccinees
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Suspected Agent. More cautious was the University of Michigan's Dr. Thomas Francis Jr., grand evaluator of the 1954 Salk vaccine trials. He warned against indiscriminately beginning vaccination programs (i.e., giving the first of two shots) until the return of cold weather. Local health officers, he said, must weigh...
Drs. Scheele and Shannon of P.H.S. gave short shrift to the Salk straight-line inactivation theory. It simply does not work that way in practice, they said: a minute quantity of live.virus may always remain in the vaccine. However, they hastened to add, the vaccine can be made so safe...
The P.H.S.'s top men were not entirely satisfied with formaldehyde as the killing agent: ironically, it may actually favor the clumping of virus particles that makes a vaccine unsafe. And they had little patience with the Mahoney strain (which has caused most of the polio in the Cutter...
Boil It Down. Yet another change, in the method of manufacture, was recommended by Pediatrician Joseph Stokes Jr. He was worried about the random sampling in huge lots of vaccine. Philadelphia's Children's Hospital has a method, he said, of reducing seven or eight gallons of virus...
Cincinnati's Dr. Albert Sabin, outspoken champion of a live-virus vaccine (TIME, May 23), suggested that all three paralysis-causing strains used in the Salk preparation be thrown out. In their place he would put nonvirulent strains, which may be found in nature or "bred" selectively in the...