Word: vaccinees
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Creating New Incentives Even so, no matter how hard businesses look or how creatively they think, there are some problems in the world that aren't amenable to solution by existing market incentives. Malaria is a great example: the people who most need new drugs or a vaccine are the...
The decision did not come as a complete surprise, since a similar and widely publicized vaccine developed by Merck failed to prevent infection or control HIV replication in a trial last year. At issue is the fact that researchers still don't know exactly how the body defends against HIV...
The trial that Fauci canceled last week was already a slimmed down version of the original 8,500-person study that government health officials had planned - until the Merck vaccine failed last fall. In a trial of 3,000 volunteers, Merck's vaccine appeared to increase risk of HIV infection...
The government's trial of its vaccine, PAVE, for Partnership for AIDS Vaccine Evaluation, was to have included only people with low levels of cold-virus antibodies, but Fauci argues that any information that could have been gleaned even from the smaller trial might not have proved useful. "Even pared...
So far, he says, the best way to answer that question is by narrowing the focus of a vaccine study to see if it can do one thing: reduce the viral load in someone infected with HIV. If a vaccine can do that, it's worth looking at more closely...