Word: valium
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Dates: during 1960-1969
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...Jack Miller noted that the widely used "major tranquilizer," chlorpromazine (Thorazine), has been shown to produce breaks in a few cases, and even the antihistamine diphenhydramine (Benadryl) in one case. Western Reserve's Dr. Mor ton Stenchever added the popular minor tranquilizers chlordiazepoxide and diazepam (Librium and Valium) to the list as causing breaks in animal cells, though this effect has not yet been confirmed in human patients. The antibiotics have not been shown to cause breaks, except for two compounds used only for advanced cancer. But the heart stimulant digitoxin causes breaks, said Buffalo's Dr. Maimon...
...drug that Dr. D. O. Nutter and Dr. R. A. Massumi recommend is diazepam, which under its trade name, Valium, is among the best-known, best-selling tranquilizers in the world today. Psychiatric patients take it by swallowing tablets, but the G.W. doctors recommend giving it by intravenous injection to patients with heartbeat abnormalities. As a result, they say, the patients are sedated gently but so deeply that they wake up with no memory of the jolting shock, and with heartbeats restored to normal...
...Sources. Dr. Carl F. Essig Jr. of the U.S. Public Health Service's Addiction Research Center in Lexington, Ky., listed five "minor tranquilizers," in addition to meprobamate and chlordiazepoxide, that can lead to intoxication or dependence: glutethimide (Doriden), ethchlorvynol (Placidyl), ethinamate (Valmid), methyprylon (Noludar) and diazepam (Valium). Excess use of any of these, said Essig, may cause drowsiness, difficulty in thinking, and incoordination of movement. The effects are similar to those of barbiturates and alcohol, and, like these, the newer drugs may contribute to traffic accidents, injuries from falls, interference with work and violent behavior...