Word: vane
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...honor, the Nobel Prize in Medicine. The 66-year-old Swede shared the award and $157,500 with two other pioneers of PG research: Bengt Samuelsson, 48, a former student of Bergström's and his colleague at Stockholm's Karolinska Institute, and British Pharmacologist John Vane, 55, of Wellcome Research Laboratories in Beckenham, England. All three received the news in Boston, where they were helping to celebrate Harvard Medical School's bicentennial. All three professed surprise at the early-morning call from Stockholm. Though Bergstrom is chairman of the Nobel Foundation, the post is largely...
...antagonistic pairs. One, for example, lowers blood pressure, while another raises it. One dilates bronchial tubes, a second constricts them. One promotes the inflammatory process, another inhibits it. A type called thromboxanes, discovered in platelets by Samuelsson in 1973, helps blood to clot; prostacyclin, a PG identified by Vane in 1976, is the most powerful natural inhibitor of clotting...
...cervix and stimulate labor for births and abortions. Compounds that block PG formation have been used to relieve pain caused by gallstones and menstruation. In fact, the most common pain reliever of all, aspirin, produces its effect by blocking the synthesis of certain prostaglandins, a discovery made by Vane in 1971 that helped resolve the longstanding mystery of how aspirin works...
...absolutely shocked by the news," said Vane, speaking for the group. "We will hold a symposium" on how to use the $157,000 prize, Bergstrom later added...
...three have had an affiliation with the University. Bergstrom received a Harvard honorary degree in 1976, Vane was a visiting professor in medicine about 10 years ago, and Samuelsson did post-doctoral research 20 years ago with E.J. Corey, now Emory Professor of Organic Chemistry...