Word: variants
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...study by a team of researchers at Harvard Medical School found a correlation between a genetic variant and a higher risk for coronary artery disease among people with diabetes and poor glucose control. Previous studies had found a relationship between the variant on chromosome 9p21 and coronary artery disease in the general population. This new study, which was published in the November 26 issue of the Journal of the American Medical Association, was the first of its kind because it focused on people with diabetes, rather than the general population. “Diabetes is one of the strongest cardiovascular...
How/why is this situation different from investors simply losing their money because of bad judgment about what to invest in? Can I get bailed out when my portfolio tanks? It's a variant on the old saw (often attributed to J. Paul Getty, although I'm sure somebody must have said something like it before him): "If you owe the bank $100, that's your problem. If you owe the bank $100 million, that's the bank's problem." Leveraged financial institutions (banks, investment banks, hedge funds) make investments with lots of borrowed money, so when their portfolios tank they...
...Thai immigrant friends and family members of the two men—are about to open a new restaurant called Shabu Square, which will come to 97 Winthrop Street in the middle of next month. The restaurant will feature “shabu-shabu,” a variant of hot pot that has been popularized in the Boston area in recent months. Shabu-shabu is cooked by dipping raw ingredients, primarily vegetables and thinly sliced beef, into a simmering metal pot of stock placed at the center of each table. Having first met in 1990 at Montien?...
...that reflected the makeup of the general Caucasian population: Specifically, they exhibited a range of variations on the FTO gene, which previous studies have associated with obesity and high body mass index, or BMI. Experts say about half of all people of European descent possess at least one "heavy" variant of the FTO gene. Within the Amish study group, some volunteers had two copies of a fattening variant; these people were 67% more likely to be obese and were on average 7 lbs. heavier than people without any copies of this form of the gene...
...researchers also discovered a subgroup of volunteers who had two copies of the heavy FTO variant, but still managed to avoid being fat. Their simple trick? Exercise. Rampersaud found that the most physically active men and women in the study were able to stay within a normal BMI range, despite their genetic predisposition; other people with the same gene variants, who were relatively inactive, were overweight. "This is the first time that we can show the direct gene-environment interaction for a gene related to obesity," Rampersaud says. "It re-emphasizes the role that physical activity plays in our daily...