Word: vascularized
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...work has been focused on the problems of what controls the growth of the microvesicles in the body," he said. "In the past 25 years, it has been discovered that tumors [in the body] must recruit from the host vascular endothelial cells...and without, virtually all tumors remain stuck, sometimes for years, at a small size...
Without blood vessels as feeding tubes, the tumors are malnourished and cannot spread throughout the body. Vascular endothelial cells make up a layer of cells that line blood vessels...
...angiogenic, the tumors become very dangerous and potentially lethal [and grow aggressively,]" Folkman said. "The proteins which the tumor cells deploy to recruit the vascular endothelial cells began to be identified 12 years...
About two years ago, it was discovered that tumor growth could be slowed almost completely by using normal proteins to signal the vascular endothelial cells which line blood vessels...
...researchers are sanguine about the future of gene therapy. To date, they have injected about 1,500 patients with some form of altered genes as part of the more than 200 gene-therapy trials taking place worldwide. Among the 30-odd illnesses targeted in these trials are cystic fibrosis, vascular disease and 15 forms of cancer...