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...addition to information systems, Millennium has been an avid proponent of automation, such as the techniques of combinatorial chemistry employed by Vertex...

Author: By Nicholas A. Nash, CRIMSON STAFF WRITER | Title: Start-Ups at Cutting Edge of Science Innovations | 4/14/1998 | See Source »

...Vertex scientists attacked the HIV protease with different drug candidates, using combinatorial chemistry to produce thousands of subtle variations of the computer's best guess. Combinatorial chemistry, explains Harvard Professor of Chemistry Gregory L. Verdine, "is a technology that allows one to make thousands to millions of organic compounds of defined structures in a very rapid period of time...

Author: By Nicholas A. Nash, CRIMSON STAFF WRITER | Title: Start-Ups at Cutting Edge of Science Innovations | 4/14/1998 | See Source »

...says Brum, Vertex had identified a likely anti-AIDS drug candidate--code-named VX-478--and signed an $42 million agreement with Glaxo-Wellcome to market and develop the compound under the brand name Amprenavir. Clinical trials began in February, 1995, and approval from the Food and Drug Administration (FDA) is expected...

Author: By Nicholas A. Nash, CRIMSON STAFF WRITER | Title: Start-Ups at Cutting Edge of Science Innovations | 4/14/1998 | See Source »

Three blocks away from Vertex, at 640 Memorial Drive, another new pharmaceutical company is developing tools and techniques that are redefining the way the industry searches for drugs...

Author: By Nicholas A. Nash, CRIMSON STAFF WRITER | Title: Start-Ups at Cutting Edge of Science Innovations | 4/14/1998 | See Source »

...like Vertex, Millennium itself aspires to become a full-fledged pharmaceutical company and has several proprietary drug discovery efforts underway...

Author: By Nicholas A. Nash, CRIMSON STAFF WRITER | Title: Start-Ups at Cutting Edge of Science Innovations | 4/14/1998 | See Source »

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