Word: viagra
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...While Viagra doesn't work for every impotent man, it does work for up to 80% of them. "There appears to be no group that has been tested that has a zero response," says urologist Dr. Harin Padma-Nathan of the University of Southern California. Even men with the most severe forms of impotence--spinal-injury victims, diabetics, those who have undergone prostate-cancer surgery--have responded...
...Viagra's effects on the hydraulics of male sexuality are pretty straightforward. Originally developed as a heart medication, the drug works directly on the blood vessels, blocking an enzyme called phosphodiesterase. This enzyme prevents the release of certain neurotransmitters--most notably one called cyclic GMP--that cause the smooth muscles surrounding arteries to relax, allowing the arteries to expand. When this occurs in penile arteries, it leads to engorgement, which leads to erection...
Irwin Goldstein could hardly wait for the FDA to approve Viagra. The renowned Boston University urologist is so excited about last week's approval of the first-ever impotence pill for men that he is opening a new sexual-dysfunction clinic, and will soon begin prescribing the drug--for women...
...Viagra trials in women are already under way in Europe. In April the FDA is holding an invitation-only meeting of scientists and pharmaceutical executives to discuss possible testing and use of the drug in women in the U.S. And in June leading sex researchers will devote their annual meeting in Cape Cod to discussing how a range of impotence drugs might be tested in female patients. If the medications prove effective, they could offer women a safer alternative to the current best weapon against female sexual dysfunction, hormone-replacement therapy, which carries a slightly increased risk of cancer. Meanwhile...
...million American men estimated to suffer impotence at some point in their lives, the pill is a godsend, as it should be for Pfizer: analysts estimate Viagra's sales could reach $500 million by 2003. Pfizer's stock, meanwhile, was, um, rising slowly on the news, reaching 95 7/16 at midday...