Word: vigneaud
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Dates: during 1940-1949
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...Vincent du Vigneaud, 47, Cornell University Medical College biochemist, "for advancing the frontiers of our knowledge of fundamental living processes." His specialty: the part played by certain chemicals in the body's metabolism...
...blue-green mold, Penicillium notatum, which excretes penicillin, has a laboratory rival. Last week a biochemical team led by Dr. Vincent du Vigneaud of the New York Hospital-Cornell Medical...
...general method, as in most syntheses, was to break down natural penicillin-G into simpler compounds which could be made artificially, then try to make these combine into penicillin. Dr. du Vigneaud and his associates started (as others had before them) with two decomposition products-dextro-penicilla-mine hydrochloride and 2-benzyl-4-meth-oxymethylene-5(4)-oxazolone. Over & over again they made them combine under different conditions...
Cheaper & Better? Dr. du Vigneaud does not claim that this process can compete economically at present with the vats of slimy blue-green mold which produce natural penicillin. But he points out that synthetic methods usually become more efficient with practice and as they are better understood. Eventually, synthetic penicillin may be cheap enough to treat the poorest patient...
This fantastic vitamin was isolated in 1936 by Professor Fritz Kögl of Utrecht, Holland but Biochemist Vincent Du Vigneaud of Cornell and his colleagues identified it as an animal vitamin in 1940. The possible molecular patterns ran into millions. Last January, Dr. Du Vigneaud and colleagues were able to announce that the possible molecular patterns had been reduced to five; then when the position of the nitrogen atoms was ascertained, these were...