Word: vioxx
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...side effects. The FDA has approved Deramaxx, the first animal drug to target the COX-2 enzyme, responsible for arthritic pain, while sparing the COX-1 enzyme, which helps dogs (and people) protect their stomach linings. This relief method puts Deramaxx in the same class as Celebrex (Pfizer) and Vioxx (Merck), which are for humans. Vets expect Deramaxx to cut into sales of Pfizer's Rimadyl and Wyeth's EtoGesic, which dominate the $150 million U.S. dog-arthritis market. Deramaxx will cost about $30 a month. Novartis plans to release it soon worldwide...
...your doctor decide that you should start taking low-dose aspirin therapy, be sure you use the right pills. Although there is reason to suspect that other anti-inflammatory drugs, such as Advil and Motrin or the newer COX-2 inhibitors Vioxx and Celebrex, might offer similar protection, only aspirin has been rigorously tested. Tylenol (acetaminophen) is not an anti-inflammatory, so don't expect it to protect you against colon or any other cancer...
...research projects were being driven not by health questions but by financial considerations - a demand for blockbuster drugs to help pay for the 60% of drugs that don't return a profit. One result: an upsurge in marketing costs. In 2000 Merck spent $161 million promoting the arthritis remedy Vioxx, more than Pepsi spent advertising its soft drink. The big American drug giants in recent years have been outpacing European pharmaceutical companies, once the world's most successful. In 1990 Europe had the largest market share for drug sales, while today America has 47% of the market, nearly double...
...Tylenol) are often all that's necessary to control their symptoms. Things become more complicated when inflammation is involved. Old standbys like aspirin or ibuprofen are pretty good anti-inflammatories, but long-term use can trigger dangerous side effects like internal bleeding. Newer drugs, such as COX-2 inhibitors Vioxx and Celebrex, are safer but no substitute for some of the long-term changes you may need to make...
Researchers found that most of the increase came from just a few drugs, including the anti-inflammatory Vioxx, the antiulcer drug Prilosec and the antihistamine Claritin. These drugs lend themselves to so-called direct-to-consumer (DTC) promotion, researchers said, because they treat common chronic conditions and have relatively mild side effects that do not require long disclaimers...