Word: vioxx
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...took up Tai Chi and learned how to breathe deeply using her abdominal muscles. These pain- management skills enabled her to lower her dosage of morphine. But Rickhoff is the first to admit she can't make it through the day without her meds, and her powerhouse weapon was Vioxx. It helped destroy any pain, any time. Last September, when she learned that Vioxx was being pulled from the market by its manufacturer because of side effects, Rickhoff began to fret. "I knew from past experience that when I'd run out of a prescription, I would start to ache...
...plenty of company in her misery. Approximately 1 in 6 Americans suffers from chronic or recurrent pain. For many, especially the millions who suffer from inflammatory diseases like arthritis or from chronic back pain, the withdrawal of Vioxx from the market last September and the serious questions raised about the safety of the entire class of COX-2 inhibitor drugs--at last week's Food and Drug Administration (FDA) hearings and in the latest issue of the New England Journal of Medicine--represent yet another setback in the long, frustrating search for relief. "I just loved Vioxx. It was magic...
...therefore inappropriate for many patients. If the FDA adopts this strategy, it would mean the end of ads like the once ubiquitous "Celebrate!" spots for Celebrex, as black-box drugs may not be advertised directly to consumers. But there was tantalizing news for Rickhoff, Dobbs and other Vioxx devotees. By a narrow vote, the panel okayed the idea of bringing the discontinued drug back to market, and Merck, its manufacturer, said this was under consideration...
...that good news? Rickhoff isn't so sure. "I definitely feel at the mercy of the pharmaceutical companies and the FDA," she says. "It's terrible that they've scared people so much. All drugs have side effects, and some probably have much worse risks than Vioxx." Studies suggest that roughly half of Americans with chronic or recurrent pain simply do not find a good solution, and the news out of the hearings is not going to make their choices any easier. In fact, chronic pain is a leading cause of lost workdays. It costs the nation an estimated...
...cardiac effects, and the biggest problem you have is some constipation," which you can treat. On the other hand, Palmer believes that the COX-2 drugs are much safer in the young than in the old. "I'll bet if you break down all those Bextra, Celebrex and Vioxx studies and look at the age group under 40 vs. the age group over 70, you're going to see dramatic differences." The problem, she says, is that most drug studies treat patients from 18 to 80 as a single group...