Word: virally
(lookup in dictionary)
(lookup stats)
Dates: during 1960-1969
Sort By: most recent first
(reverse)
...years, the one clear mark of the virus was this ability to slip invisibly through porcelain filters. In those four decades, without waiting to see what a virus looked like, brilliant men did brilliant things about viruses and viral diseases. At Manhattan's Rockefeller Institute, Dr. Peyton Rous in 1910 proved that a filterable virus is the cause of sarcoma (a kind of cancer) in chickens. At Harvard and then at the Rockefeller Foundation, South Africa-born Max Theiler performed the delicate and dangerous feat of getting yellow-fever virus to grow in the brains of mice. With infinite...
...Vaccination Mechanism. The most practical results so far of virological research are vaccines, and vaccines depend on the basic concept of viral structure as a nucleic-acid core with a protein overcoat. The coat is a foreign substance to the body it invades, and in the higher animals, including man, the system fights back by making antibodies that gang up on a virus particle, surround it and neutralize it. Unhappily, it takes days or weeks for the body to mobilize its antibody police, so the first viral invasion is likely to succeed and make the invaded victim sick...
...could see that the cells were damaged and began to fall apart as the virus multiplied. Others had seen this phenomenon; to the thoughtful Dr. Enders its significance eventually became clear and astonishingly simple: the nature and amount of cell damage were indexes to the nature and amount of viral activity. "It seems incredibly obvious now," he says...
...that in some unpredictable cases, a molecule of viral nucleic acid, without its protein overcoat, so closely resembles a gene that it can slip into the cell's chromosomal lineup, displacing a normal gene, and make the cell reproduce abnormally. Most of the resulting abnormal cells would probably die, but a few might retain the power to run wild and perpetuate themselves as cancer...
...victim's susceptible cells in the meantime? London's Dr. Alick Isaacs last year found a partial answer. Virus-infected cells produce a substance that Isaacs calls interferon, which spreads to neighboring, uninfected cells. With their interferon guard up, these cells are unusually resistant to viral invasion...