Word: virus
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Shedding greater light on the human body’s first-line defense against the flu virus, the researchers found that the family of flu-fighting proteins—called the interferon-inducible transmembrane (IFITM) proteins—prevented or slowed down most virus particles from infecting human cells early in the lifecycle of the virus. The team reported its findings in an online journal on Thursday...
...Most of the time we find things that the virus needs,” said Abraham L. Brass, instructor in medicine at Harvard Medical School and Mass. General Hospital, who helped lead the study. “This time we found something our cells are using to resist the virus...
...which the study took place. With this understanding, Elledge and his team systematically deactivated every gene in the human genome—testing some 20,000 different genes—using new RNA interference technology, hoping to determine the genes in the host cells that the virus relied upon for infection...
...researchers, who had already used this same process in studies of HIV and the hepatitis C virus, hoped to find that some of the treated cells could not be infected with the influenza virus, which would suggest that the virus needed the deactivated gene to function. Instead, the researchers were surprised to find that the rate of infection increased dramatically when certain genes were deactivated...
...study, which involved 370 healthy children ages six months to nine years in Australia, researchers immunized half of the group with two doses of vaccine, each containing 15 micrograms (mcg) of the virus antigen. The other half received two doses containing 30 mcg of the antigen each. In both cases, the second dose was given 21 days after the first. The researchers found that 21 days after receiving only one shot, 92.5% of children in the 15-mcg-dose group and 98% of those receiving the higher dose had generated sufficient antibodies against H1N1...