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...will convene an expert panel on April 29 to attempt to answer that question, but one way to begin is to look at where the virus originated. Epidemiologists appear to be homing in on a possible ground zero in the Mexican Gulf Coast state of Veracruz, in a town called Perote, which is home to a large pig farm owned by the U.S. company Smithfield Foods. Flu-like cases began popping up there in early April, before the first confirmed case in Mexico on April...

Author: /time Magazine | Title: Mexico's Mystery: Why Is Swine Flu Deadlier There? | 4/29/2009 | See Source »

...truth is that even though the virus is referred to as swine flu, researchers do not yet know for sure that the A/H1N1 virus actually originated in pigs. There's been no evidence yet of pigs getting sick in either Mexico or the U.S. (Despite several countries' bans on pork imports, it's important to remember that the disease cannot be contracted by eating pork.) The original reservoir for flu viruses is actually wild birds, which can spread infection to domestic birds and people - as we saw with the H5N1 avian flu in Asia - and to pigs. Pigs make particularly...

Author: /time Magazine | Title: Mexico's Mystery: Why Is Swine Flu Deadlier There? | 4/29/2009 | See Source »

...recent years, since the ongoing H5N1 bird-flu virus first surfaced, health officials have focused mostly on Asia as the breeding ground for the world's next pandemic flu virus. But Daszak points out that Mexico, where people, pigs and poultry can exist in close proximity, is an overlooked hot spot for new viruses. Given the booming global livestock trade - more than 1.5 billion live animals have been shipped to the U.S. from all over the world in the past decade - it's possible that the A/H1N1 virus originated in an Asian bird that was exported to Mexico, where...

Author: /time Magazine | Title: Mexico's Mystery: Why Is Swine Flu Deadlier There? | 4/29/2009 | See Source »

...that the swine-flu virus seems well established in human beings, containment is no longer an option. The public health response must be to slow the spread, which means getting a better handle on the virus. While the difference in severity between Mexico and U.S. cases would suggest that there are different viruses affecting the two countries, researchers have genetically sequenced swine-flu viruses from both Mexican and American victims, and "we see no difference in the viruses infecting sick people and less-sick people," said Fukuda. And even if there were genetic differences, it wouldn't necessarily mean much...

Author: /time Magazine | Title: Mexico's Mystery: Why Is Swine Flu Deadlier There? | 4/29/2009 | See Source »

...also possible that A/H1N1 began life in Mexico especially virulent - that country has apparently been grappling with the virus for weeks longer than the U.S. has - and evolved to become less dangerous by the time it crossed the border. That would not be an unusual evolutionary device, since viruses that are too deadly cannot survive if they kill off their host before being given a chance to spread. "It's fairly common in epidemics to see a trade-off between the ability to cause severe death and transmissibility," says Steven Kleiboeker, a virologist and the chief scientific officer for ViraCor...

Author: /time Magazine | Title: Mexico's Mystery: Why Is Swine Flu Deadlier There? | 4/29/2009 | See Source »

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