Word: viruses
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Dates: during 1980-1989
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...procedure was routine, similar to one undergone each year by up to 4 million Americans -- victims of auto accidents, those recovering from operations, cancer patients and others. But this transfusion contained the seeds of tragedy: unknown to anyone at the time, the blood was infected with HIV, the virus that causes AIDS (acquired immunodeficiency syndrome). The next year the patient developed an AIDS-related form of pneumonia, and he died in 1984. His wife tested positive for the AIDS antibodies, and was later diagnosed as having a type of cancer associated with AIDS. She too has died...
MacDonald speculates that the influenza virus can injure the throat or lungs in a way that favors the growth of S. aureus. Though the complication appears to be rare, it is urgent that doctors be aware of it, says TSS Expert Bruce Dan, in an editorial that accompanied MacDonald's paper. Early recognition and treatment of the syndrome "is the most important factor in being able to prevent fatalities," says Dan. "It behooves all physicians to be on the lookout for any influenza patient whose condition suddenly worsens...
...session, which featured Popadiuk's grilling, went even more smoothly. One personal touch that Reagan never got the chance to use came in answer to a practice question on AIDS. He replied by telling a story he heard from a friend about a man who had contracted the virus from a blood transfusion; within a year both the man and his wife had died. "I'm not sure I should tell this," Reagan said. "You should tell it," responded Howard Baker. "It's you. It shows the feeling you have for people in trouble, and it's touching because...
Most animals have little to fear from the lethal AIDS virus. That is good for them but not for human beings, since other species are of little use to medical researchers seeking treatments and vaccines for the deadly disease. The limited value of research on baboons and chimpanzees, among other beasts, creates an urgency to move swiftly to tests on humans. Last week, after months of rumors within the scientific community, it was confirmed that this dramatic leap has been taken in vaccine research. In a letter in the British journal Nature, Dr. Daniel Zagury, an AIDS investigator...
Actually the personal risk to Zagury was probably quite small. The vaccine he used, based on the work of NIH Immunologist Bernard Moss, contained only a tiny portion of genetic material from the AIDS virus. This material was inserted into the genes of a larger, harmless virus, which served as a carrier. (The larger virus was vaccinia, once commonly used to prevent smallpox.) When tested in baboons and a chimp for one year, this hybrid stimulated the animals to produce antibodies not only to vaccinia but to the AIDS virus, with no apparent side effects...