Word: viruses
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...KONG Bird Flu Hong Kong's government ordered the "depopulation" of the territory's estimated 1.2 million poultry as a new and highly virulent strain of avian flu was discovered. All market poultry stalls were shut down, and imports of live birds from China were halted. The new H5N1 virus is genetically different from the virus that led to the slaughter of all Hong Kong's poultry - and six human deaths...
...drugs represent a whole new approach to fighting the disease. The most commonly used drugs on the market today target the HIV virus once it has already invaded immune-system cells called CD4s. But the new class of drugs, called entry inhibitors, is designed to keep the virus from ever entering the cell walls - and therefore, scientists hope, from duplicating themselves inside the cell. And that means new hope for everyone who's concerned about AIDS, especially those who've developed resistance to existing drug courses. "This is great news, especially for HIV-positive patients," Dr. Margaret Fischl, Director...
...drugs, new ways to attack the virus...
...entry inhibitors: Fusion inhibitors, attachment inhibitors and co-receptor inhibitors. And while each works in a slightly different way, all entry inhibitors work on the same principle: The longer the cells can deflect attacks from HIV, the longer other drugs will have to work on destroying the existing virus already inside the cell...
...Fusion inhibitors are the rising stars of the entry inhibitor group. Designed to keep the HIV virus from fusing to the cell wall, fusion inhibitors include compounds called T-20 and T-1249. The first compound, T-20, appears to be at the head of the class, so to speak; researchers report low toxicity among test cases, and relatively mild side effects like soreness and inflammation at the injection site, dizziness and nausea. For the needle-phobic, T-20 may cause a few problems - patients are required to inject themselves twice a day. But for most, even multiple injections...