Word: vivax
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Dates: during 1940-1949
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Early last year a team of chemists, biologists and veterinarians set out for Africa to attack the trypanosomes in their native stronghold. A single dose cured cattle infected with T. congolense and T. vivax, two worst forms of the disease. It also worked well against other forms in cattle, horses, dogs, hogs and camels. Healthy animals appear immunized against infection for as much as six months...
What could be done about malarial mosquitoes which escape DDT campaigns? Four war-born drugs help their victims, the conference was told: 1) chloroquine, more active than quinine or atabrine, and much less toxic; 2) pentaquine, which has reduced the relapse rate in the vivax form of malaria from 98% to 25%; 3) iso-pentaquine, a variant of pentaquine, so far tried on only 100 cases; 4) Paludrine, which controls vivax malaria with a single dose...
Next problem was to find a human to check the experiment on. The parasite that causes monkey malaria (Plasmodium cynomolgi) is like the parasite that causes most human malaria (Plasmodlum vivax"). He found a mental patient who was about to be given malaria anyway for treatment of general paralysis. The patient and his wife agreed that doctors could take out a small piece of his liver by a minor operation, seven days after he had been bitten by infected mosquitoes. At 5 o'clock one morning Dr. Shortt got the sliver of liver, rushed to his laboratory and worked...
...researchers reported that they were getting warm. In a paper so important that it got a prize from the American Association for the Advancement of Science, they announced that they had bred in a test tube two types of animalcules. One causes malaria in monkeys and the other (Plasmodium vivax...
...protozoa which cause the disease are carried by about 60 kinds of mosquitoes and are of four main varieties, each producing its own form of malaria: 1) Plasmodium vivax produces the mildest disease, benign tertian malaria; 2) P. malariae bring on quartan malaria, the most difficult to eradicate; 3) P. falciparum produces dangerous malignant tertian malaria; 4) P. ovale produces symptoms similar to those of benign tertian malaria...