Word: warfarin
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Dates: during 1990-1999
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...heart allows small amounts of blood to pool in the atria, where the blood can form clots that can travel through the brain, causing a stroke. The risk is greatest for folks 65 and older, who are often given blood thinners like aspirin and the prescription drug warfarin to lessen the risk. But Bradley is 56. And in a Dec. 9 letter to the candidate, his doctor reported that the occasional irregular heartbeat "does not, in any way, interfere with [his] ability to function...
PILL PROBLEM If you're on the blood thinner warfarin, taking 1,300 mg of acetaminophen--equivalent to four regular Tylenol--or more a day can raise the risk of hemorrhage...
...Warfarin, known in North America by its trade name Coumadin, works by blocking Vitamin K-de-pendent factors involved in clotting activation. But because warfarin slows clotting, the drug can be dangerous to patients prone to ulcers or head injuries, which can cause life-threatening internal bleeding...
...warfarin is used more widely in less controlled conditions, it may cause more trouble than observed in clinical trials," Singer said in an interview yesterday. "On balance, the message that comes out of these remarkable trials is that every patient with chronic atrial fibrillation should give warfarin a good look...
...effects of aspirin are hardly comparable to warfarin for this condition," he said. "I'm skeptical that there's much benefit...