Word: warfarin
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Dates: during 2000-2009
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...separate study, researchers at the University of Chicago found that ginseng, which is widely used to boost energy, can sometimes do more harm than good. In 20 volunteers, taking the herb disrupted the effects of the clot-busting drug warfarin, prescribed for millions of heart-attack patients. Because warfarin's dosage must be precise--too little can lead to clotting and too much can cause bleeding--any substance that alters its potency can have serious consequences...
...other states, the brand-name companies have retained the upper hand. DuPont's allies in Florida, for instance, killed this year's effort by its rival Barr to let pharmacists substitute generics, including its blood thinner warfarin, for four brand-name drugs unless a doctor objects. Minutes after the state senate passed a bill backing Barr's plan in April, a flotilla of DuPont lobbyists converged on Speaker John Thrasher's office. Thrasher had earlier asked Republicans studying the bill to oppose it. Now he refused to let it come up for a vote. With the clock running, allies...
Three years ago in North Carolina, DuPont helped ram through the legislature a bill requiring doctor's approval for the substitution of generics like Barr's warfarin. "We are only concerned about patient safety," says DuPont spokesman Thomas Barry. Some physicians support DuPont's position because they say warfarin is a tricky drug and doses must be carefully calibrated. The implication is that the brand names do a better job of that. But the FDA says the generic version is safe and has admonished DuPont more than once for stoking false fears in its promotion of Coumadin...
...sides worked out a compromise to give immediate approval to most generics. Barr's lobbyists relaxed. Too soon, it turns out. A month ago, an amendment was quietly tacked onto a new bill to help the poor pay for prescriptions. The rider makes it harder to substitute generics like warfarin. Ryan is set to sign the bill...