Word: warfarin
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Investigators at the Massachusetts General Hospital (MGH) received a five-year grant from a division of the National Institutes of Health last July 1 to explore the benefits and possible side effects of "warfarin," a potent anticoagulant (anticlotting) drug...
...objective of the study is to determine if the benefits of warfarin outweigh the risks due to complications such as bleeding," said Dr. Robert A. Hughes, director of the MGH's Anticoagulant Therapy Unit...
...Warfarin has been given to some subgroups of AF patients' over the past 30 years with varying degrees of success. There has been no well-designed study with absolute proof to convince doctors that the drug really works, Hughes said...
...fact that bats, like rats, are more sensitive than most mammals to the hemorrhagic properties of anticoagulants. These are the chemicals used medicinally to protect human victims of heart attacks and strokes against the recurrence of dangerous blood clotting; overdoses can cause fatal internal bleeding. The best known anticoagulant, warfarin, is used in calculated overdoses as a rat poison. In 1968 a two-nation team began work at the National Livestock Research Institute in Mexico City and the U.S. Department of the Interior's Wildlife Research Center in Denver to try to kill bats with an anticoagulant. Choosing...
...aren't exactly alarmed-the Ministry of Agriculture is never alarmed -but we are working very hard to find an alternative to warfarin," says a British government official. Even so, the rats have a final defense that has made a fool of man since the combat began. The average female produces up to twelve litters a year, and in each litter are ten ravenous young rats...