Word: warning
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ABANDON HOPE, ALL YE WHO ENTER HERE. That legendary inscription over the gate of hell, as described in Dante's Inferno, appeared last week on a sign that New York Democrat Stephen Solarz posted at a meeting of the House Budget Committee. His point was to warn his fellow liberals that they have no chance of stopping a congressional drive to balance next year's budget, in part by cuts in Government social spending which the liberals find downright hellish...
Despite all the recent achievements, the growing excitement and the favorable early test results, the verdict is not yet in on interferon. Even IF's most fervent advocates warn against prematurely raising the hopes of cancer victims and their families. They appraise IF's prospects in the subjunctive, peppering their comments with "if" and "would" and "could." Were interferon finally to prove an effective cancer drug, there would still be a long way to go. At least a few?and possibly quite a few?years will pass before it becomes widely available. "In terms of research," says Dr. Ernest Borden...
Enter interferon. The initial infection somehow triggers the first cell into producing IF. In turn, the interferon assumes the role of an intercellular messenger; it passes through the cell membrane and moves on to warn surrounding cells of the viral invasion. The healthy cells respond by producing antiviral proteins, which meet any invader head on. The entering virus will not be able to replicate within the new cell; if it does manage to reproduce, its progeny find that they are unable to leave the cell. The cycle of infection is broken...
...effect, it was like starting an armaments program without fully understanding how the weaponry works. If interferon is the body's Paul Revere, designed to warn against viral invasion and stimulate the defense forces, why does it also appear to work against cancer? Though viruses are suspect in some human cancers, interferon also seems to work against tumors generally thought to be caused by nonviral agents such as radiation and chemicals...
...that Ford knew the gas tanks of the early Pintos were likely to rupture in rear-end crashes, but after a cost-benefit analysis, had decided against installing a $6.65 part that would have helped protect the tanks. Cosentino maintained that Ford then did not try hard enough to warn Pinto owners about the danger. He produced eyewitnesses who testified that the girls' Pinto had been moving at 15 to 35 m.p.h. when struck, meaning that the impact speed was equal to no more than 35 m.p.h. At that speed, Cosentino maintained, a fuel tank should not rupture...