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...better understanding of the G9a pathways could lead to the development of safer, more specific drugs. And studying the genes that control G9a itself could also help screen people at risk for cocaine addiction: those with naturally lower levels of the protein would be the ones to watch. Still, there's a lot to be learned even from further mouse studies - particularly if the work involves younger mice, unlike the adults used in Maze's research. (See the top 10 medical breakthroughs...

Author: /time Magazine | Title: How Cocaine Scrambles Genes in the Brain | 1/8/2010 | See Source »

...revamped system. Governors of both parties are complaining that reform will drive their budgets into even deeper holes, with some feeling the effects far more than others. But just how much will be riding on the states? Here's a look at four changes that lie ahead. (Watch TIME's video "Uninsured Again...

Author: /time Magazine | Title: What Health Care Reform Means for the States | 1/8/2010 | See Source »

...murder came in the middle of the government's final offensive to crush the separatist Liberation Tigers of Tamil Eelam (LTTE). The government did not brook any criticism of its conduct of the war, but even since declaring victory last May things are little improved for journalists. (Watch a video about the final days of Sri Lanka's civil...

Author: /time Magazine | Title: Sri Lanka Journalists Still on Edge After Editor's Death | 1/7/2010 | See Source »

...Given al-Qaeda's love of head fakes, the official wonders what percentage of the 550,000 names on the U.S. terrorism watch list might be decoys intended to jam American databases and allow more furtive or budding extremists to get lost in the mass of information. But even if there is a high number of errant names on such lists, he acknowledges, they are a necessary evil - for now. Although the U.S. intelligence systems are imperfect and occasionally get swamped, casting as wide a net as possible is still the best hope for identifying the largest number of would...

Author: /time Magazine | Title: Flight 253: Too Much Intelligence to Blame? | 1/7/2010 | See Source »

...police to hold a swift and thorough inquiry. But like all the inquiries you have ordered in the past, nothing will come of this one, too." The widely circulated piece sent shockwaves beyond Sri Lanka. "You will never be allowed to forget that my death took place under your watch," it read. (Read a TIME interview with Rajapaksa...

Author: /time Magazine | Title: Sri Lanka Journalists Still on Edge After Editor's Death | 1/7/2010 | See Source »

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