Word: waterland
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...importance of DNA methylation in altering the physical characteristics of an organism was proposed in the 1970s, yet it wasn't until 2003 that anyone experimented with DNA methylation quite as dramatically as Duke University oncologist Randy Jirtle and one of his postdoctoral students, Robert Waterland, did. That year, they conducted an elegant experiment on mice with a uniquely regulated agouti gene - a gene that gives mice yellow coats and a propensity for obesity and diabetes when expressed continuously. Jirtle's team fed one group of pregnant agouti mice a diet rich in B vitamins (folic acid and vitamin...
...vitamins acted as methyl donors: they caused methyl groups to attach more frequently to the agouti gene in utero, thereby altering its expression. And so without altering the genomic structure of mouse DNA - simply by furnishing B vitamins - Jirtle and Waterland got agouti mothers to produce healthy brown pups that were of normal weight and not prone to diabetes...
...secret ... Swift is an enigma himself. London-born, Cambridge-taught, married with no children, he doesn't talk much about his methods or motives. He did, however, pursue a Ph.D. in Victorian literature, which may explain the handcrafted antique seriousness of his best work. That would include 1983's Waterland, a sweeping, impressively detailed family saga of fortune and folly. Swift's version was watered down into a movie with Jeremy Irons and Ethan Hawke, but the novel made the short list for the Booker Prize. Swift finally won the Booker in 1996 for Last Orders, an equally powerful tale...
...Open Forum could be used to support the meeting of the minds within the dutch project digital waterland," wrote one person who identified herself as Joop Veenis...
Loews Harvard Square. 10 Church St.,Cambridge. 864-4580. Through Thursday, Dec. 10.The Lover at 12:50, 3:05, 5:20, 7:40 and 10 p.m.and 12:10 a.m. Waterland at 1, 3:15, 5:25, 7:45and 10:10 p.m. and 12:10 a.m. River Runs ThroughIt at 1:30, 4:15, 7:20 and 9:50 p.m. GlengarryGlen Ross at 1, 3:10, 5:20, 7:40 and 9:55 p.m. and12 a.m. Last of the Mohicans at 1:10, 4, 7:15 and10 p.m. and 12:20 a.m. Rocky Horror...