Word: weighted
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Dates: during 2000-2009
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...Biggie was notorious, James is nice. An oversize comic in the mold of Fatty Arbuckle, Jackie Leonard, Buddy Hackett, Rodney Dangerfield and Jackie Gleason, James is different in not using his weight as an excuse for high-pressure comedy - a giant tea kettle ready to blow its top. The star of TV's The King of Queens, he's a Ralph Kramden without anger issues. In Paul Blart, as in I Now Pronounce You Chuck & Larry (where he starred with Adam Sandler, this film's executive producer), James gets laughs by underreacting to the humiliations the world heaps...
...they could all say they were there, to stand together and glimpse a man in the very far distance accept the full weight of their hopes. That, in the end, is the source of Obama's power. What are we willing to let him do with his office, with a power greater than the one he had when he began this day? At his national-security briefing in the morning, Obama was instructed in the use of the nuclear codes, should he ever have to launch a strike. Once he was sworn in, once the 21 guns had saluted...
...each person's ability to extract energy and store fat from food changes depending on which combination of bugs are living in the gut. Those who are morbidly obese, it seems, tend to nurture bugs that promote the fat-storage process, which might be a factor in their excessive weight gain. The bypass patients appeared to follow a similar pattern but in the opposite direction, eating less first and then developing bugs appropriate to that diet. It's not clear how the physical act of reducing food intake drives that change, nor how long-lasting the possible slimming effects...
...none of this means that downing the latest probiotic yogurts, which contain certain strains of good gut bacteria, should be the next weight-loss craze. For one thing, says DiBaise, the strains that were dominant in the normal-weight people are not the same as those promoted in the popular probiotic yogurts. Second, there is no evidence that probiotic products can do anything about weight loss; the latest scientific studies have shown only that probiotics can relieve antibiotic-related diarrhea, as well as alleviate IBS and aide regularity. "It is interesting to look at microbial flora," says Lynne McFarland...
...least, not yet. More studies are needed to follow the same people as they lose weight through diet and exercise, to see if the composition of their gut flora changes - as it did with the gastric-bypass patients. What's more, notwithstanding the seeming cause-and-effect link between gut flora and weight, that relationship can be deceiving; a third factor entirely may be causing both - a diet of highly processed foods, for instance, suggests Dr. David Katz, director of the Yale Prevention Research Center. What's more, says Katz, "regardless of the variation of gut flora in the population...