Word: weightness
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Dates: during 1990-1999
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...expected to employ a collapsing defense strategy, holding a prepared line for a time, then falling back to another prepared position until it reached an area that was finally defensible. Experts deemed it a reasonable strategy; not only is Krajina too large to defend in its entirety, but the weight of both geography and history were on their side. "They are frontiersmen," said one Western diplomat in Belgrade, who pointed out that Serbs were first sent to Krajina by the Austro-Hungarian Empire as a buffer against the Turks. "These guys were the eternal defense." On Saturday night, however...
...politically-correct answer for this broad-based retreat is that, in the post-Cold War age, we would do well to push our financial and political weight towards more pressing issues such as the advancement of our economic interests. Germany and Japan have enjoyed their outstanding economic growth, it is argued, in large part due to their non-military status; we must avoid whenever possible the exorbitant costs of international policing if we hope to partake in this prosperity. The consequences of such a policy would compromise economic and political relations as well as our strategic links abroad. Indeed, while...
...pharmaceutical company Hoffmann-LaRoche described how they plumped up lean mice by giving them unrestricted access to high-fat food. Then they administered leptin. The mice responded by cutting their food intake and shedding the extra ounces, suggesting leptin may have value in reversing more typical cases of weight gain...
What about side effects? Injections of leptin do not, as one might fear, turn lean mice into starving wretches. After losing weight, researchers from Amgen reported, normal mice stabilize both their food intake and their metabolism. Obese mice likewise reach an optimal leanness, then stop losing weight. The pattern of weight loss is also encouraging. For unlike extreme calorie restriction, which can weaken muscle, leptin appears to dissolve fat while leaving lean tissue intact. On the basis of such data, Amgen (which paid Rockefeller University $20 million for patent rights to make products based on the ob gene) has announced...
...swallow "thin pill" dieters have dreamed of for so long. To do its work, leptin would probably have to be either injected daily, like insulin, or implanted under the skin for the rest of one's life. In the laboratory experiments reported last week, the obese mice started regaining weight as soon as the injections stopped. Even with a boost from something like leptin, cautions Dr. Ahmed Kissebah, an obesity expert at the Medical College of Wisconsin, the formerly fat cannot afford to become less vigilant. "People will still have to lose weight the hard way," he predicts...