Word: willebrand
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Another bleeding disorder that is similar in its effects on patients, but totally different in inheritance and incidence is von Willebrand's disease. This is the most common of a group of clotting disorders that are transmitted by genes on some other chromosome than the x-which chromosome, remains a mystery. But it is a nonsex chromosome, so boys and girls are equally likely to inherit the defective gene...
...progress is advancing from the lab to the bedside. Factor VIII is now being extracted from human plasma and concentrated about 30 times. It is given by intravenous drip to victims of hemophilia A and von Willebrand's disease when they have crises of massive bleeding. Except in such emergencies, the usual treatment for all the clotting disorders remains a transfusion of fresh whole blood or plasma-not to replace blood that the patient has lost, but to supply the missing clotting factor and thus keep him from losing more...
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