Word: wilmut
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...Wilmut, the king of clone, will have to wait a while to claim his Nobel Prize. But it is not too early to give him the 1997 Brevity Award. His paper in Nature announcing his creation of Dolly runs fewer than three pages. (Technical notes take up part of a fourth.) Most scientific papers--most people--take three pages to clear their throat...
Even if the basic scientific procedure of creating mammals from cells that are not embryonic can be easily mastered, the routine cloning of humans is still a long way off [SPECIAL REPORT, March 10]. Using the reproductive procedure that produced embryologist Ian Wilmut's lamb Dolly requires dozens of surrogate mothers. The work of Wilmut and his colleagues is a great step toward understanding important fundamental biological processes, and it does raise serious ethical issues, but don't belittle the scientific effort by calling it "easy." JENNI HARIKRISHNA Kuala Lumpur...
Freedom vs. Fear of the Unknown: A Senate hearing room fell silent today as Senator Tom Harkin reflected with quiet passion on the furor surrounding the notion of human cloning. Dr. Ian Wilmut, who produced the cloned sheep Dolly, had told the panel that human cloning should not be all owed, since so many deformed and unviable clones would be produced in order to succeed. Comparing the eager bipartisan opposition to human cloning research to the 17th Century persecution of Galileo for his observation that the Earth revolves around the Sun, Harkin said it was wrong of President Clinton...
What enabled the Scottish team to succeed where so many others have failed was a trick so ingenious, yet so simple, that any skilled laboratory technician should be able to master it--and therein lies both the beauty and the danger: once Wilmut and his colleagues figured out how to cross that biological barrier, they ensured that others would follow. And although the Roslin researchers had to struggle for more than 10 years to achieve their breakthrough, it took political and religious leaders around the world no time at all to grasp its import: if scientists can clone sheep, they...
...this point, Wilmut and his colleagues switched to a mainstream cloning technique known as nuclear transfer. First they removed the nucleus of an unfertilized egg, or oocyte, while leaving the surrounding cytoplasm intact. Then they placed the egg next to the nucleus of a quiescent donor cell and applied gentle pulses of electricity. These pulses prompted the egg to accept the new nucleus--and all the DNA it contained--as though it were its own. They also triggered a burst of biochemical activity, jump-starting the process of cell division. A week later, the embryo that had already started growing...