Word: wilmut
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...still surprised that cloning works," says Ian Wilmut, the embryologist who led the team that created Dolly. Ten years and 15 mammalian species later, the efficiency of the process is no better than it was at Dolly's birth: only 2% to 5% of the eggs that start out as clones end up as live animals. For each clone born, hundreds of others never make it past their first days and weeks, the victims of defects in development too severe to allow them to survive...
...tough to prove, even to those outside investigators. As long as they have tissue samples from both the clone and the parent, they should be able to determine whether DNA in the nuclei of both animals' cells is identical--the first hallmark of a true clone. Ian Wilmut, the Scottish scientist who created Dolly the sheep in 1996, had to provide such samples to prove to skeptics that he had created history's first mammalian clone...
...Still, Hwang has a lot of explaining to do. He is already being investigated by his own university. And earlier this week, eight stem cell scientists, led by Dolly cloner Ian Wilmut, submitted a letter to Science, noting that ?accusations made in the press about the validity of the experiments published in South Korea are, in our opinion, best resolved within the scientific community... we encourage Hwang?s laboratory to cooperate with us to perform an independent test of his cell lines.? At stake, say the scientists, is the fledging field of stem cell science, which holds the potential...
Meanwhile, the question many researchers are asking is: What will the South Koreans do next? Hwang met last week with Scotland's Ian Wilmut, Dolly's cloner, who wants to work with the South Koreans on Lou Gehrig's disease. Similar collaborations are under way at Memorial Sloan-Kettering Cancer Center in New York City and at Johns Hopkins in Baltimore, Md. By the end of last week, however, Hwang was back at his lab in Seoul, putting even more distance between himself and the rest of the scientific world...
Cloning Scottish embryologist Ian Wilmut cultured an adult ewe's cells and implanted them in a surrogate, and on July 5, 1996, Dolly was born. Litters of cloned mice followed, and the ethical debate intensified...