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...H1N1) and preventing it from doing its job of helping the virus replicate once inside a human cell. But certain amino-acid changes in the neuraminidase can render Tamiflu ineffective. This usually happens over time following extensive prescribing of the drug, but it can also occur spontaneously. In the winter of 2007-'08, a seasonal H1N1 variant circulating in Europe did just that, catching scientists by surprise. "We really didn't see that coming," says Daniels, who was one of the first scientists to identify the change. "Suddenly, an increasing number of H1N1 isolates were Tamiflu-resistant, and the resistant...

Author: /time Magazine | Title: The Flu Hunters: Racing to Outsmart a Pandemic | 8/11/2009 | See Source »

...last winter, the game had changed. When the couple started looking at houses again, they found plenty in their price range. The western suburbs of Boise, Idaho - four- and five-year-old neighborhoods scattered among hay farms and potato fields - are no longer a favorite stomping ground of out-of-state speculators, no longer a surefire way to get rich in real estate. (See pictures of Boise's struggling housing market...

Author: /time Magazine | Title: How the Housing Market Is Fighting Its Way Back | 8/10/2009 | See Source »

After 35 years in the mortgage industry, Tom Birch took a job as a housing counselor at Boise's Neighborhood Housing Services this past winter. He spends his days meeting with people who can no longer afford their mortgage payments. It has been tough going. More than most, Birch appreciates that mortgage companies were not prepared to handle the number of cases they have seen. He also understands, again probably more than most, that foreclosure is, in certain circumstances, the right outcome...

Author: /time Magazine | Title: How the Housing Market Is Fighting Its Way Back | 8/10/2009 | See Source »

...called swine flu--will sear the history books or merely strike us a glancing blow. In just a few months, H1N1/09 has spread to nearly every country in the world, infecting so many people that the World Health Organization has officially stopped counting. In nations where it is already winter, like Argentina, H1N1/09 has caused billions of dollars in damage, and China is quarantining foreigners suspected to have the flu. In the U.S., the virus has continued to multiply in the summer--a worrisome sign, since influenza usually takes a vacation when the weather improves...

Author: /time Magazine | Title: The Moment | 8/10/2009 | See Source »

...better understand how this bug might move through the U.S. in coming months, officials have spent part of this summer monitoring the way H1N1 has been behaving during the southern hemisphere's winter months. It has been spreading fast, attendance has dropped at Patagonian ski resorts, and flu fears have crippled the Buenos Aires theater business. Across the region, countries are reporting that H1N1 has become the dominant strain of the flu season. But the most positive development is that the virus has so far not mutated - a fact that makes it possible for scientists to create a vaccine...

Author: /time Magazine | Title: Inside the Fight Against a Flu Pandemic | 8/6/2009 | See Source »

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