Word: wounded
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Dates: during 1990-1999
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...lightweights made a devastating faux pas a quarter of the Way through the race, and then wound up finishing an absurd fifth...
...wound up with the foundation of a family fortune that has since grown to around $4 billion, but troubled by a thought he was still voicing decades later: "How long do you think it'll be before they stop calling me a goddam bootlegger?" Seeking respectability and reacting against the strong anti-Semitism of the Canadian elite, he plunged into Jewish affairs, raising huge sums in the 1930s and '40s to help the Zionist founders of what became Israel. His son Edgar Sr., who became head of Seagram's U.S. operations in 1957 and of the whole company...
...Liberals," opinion, April 30, 1994) that he has "little or nothing intelligent to say about important issues." And certainly, after reading so many of his engaging, but unsatisfying arguments, such as his critique of typos in prochoice flyers, I'm not sure why I keep pouring salt on the wound. But, like him, I never learn...
...major factor, scientists believe, is a sudden drop in the cancer cell's production of thrombospondin, a protein that inhibits the growth of new blood vessels. In the normal adult, angiogenesis is not only a rare event, but one cells strive to prevent, save for special circumstances like wound healing. For blood vessels invading joints can cause arthritis, and those invading the retina of the eye can cause blindness. To prevent such damage, cells keep blood vessels at bay by pumping out thrombospondin. At a recent scientific conference, Noel Bouck, a molecular biologist from Northwestern University Medical School, stunned...
What makes MTS1 so significant is its clear role in the cell-division cycle. A cell divides not at will but in response to specific signals, such as growth factors produced by white blood cells rushing to repair a wound. These signals are picked up by receptors on the membrane of the cell and passed along -- like batons in a high-speed relay -- through the interior, all the way to a master "on" switch positioned deep in the nucleus. Not surprisingly, many oncogenes, including one called ras, the first human cancer gene ever identified, are involved in this type...