Word: woundedly
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...including heart disease, transplant rejection, stroke, arthritis, shock and cancer. Michael Gimbrone Jr., head of vascular research at Harvard Medical School, predicts "a whole new generation of therapeutic interventions." Several drugs are now being tried on humans, and early next year the first of them -- a gel that spurs wound healing -- will enter the final U.S. government approval process...
...opposite end of the spectrum are inflammatory diseases like arthritis and multiple sclerosis, in which things have got a bit too sticky. Normally, inflammation is part of the healing process. At a wound site, for example, chemical signals prompt the cells of nearby blood vessels to produce more CAMs, turning the vessels into a kind of biological flypaper that attracts platelets, leukocytes and other repair cells to the scene of destruction. Once healing is under way, the signals subside so the vessels lose their stickiness and inflammation recedes. But in a disease like arthritis, the chemical signal is always present...
Still, too much inflammation is probably better than none at all. The latter is the peculiar plight of Brooke Blanton, a 13-year-old Dallas girl who has taught researchers much of what they know about cell adhesion and wound healing. Brooke first came to doctors' attention as an infant, when her umbilicus and teething sores failed to close and became infected. Strangely, Brooke's lesions contained no pus -- the carcasses of millions of white cells that pile up at infection sites -- even though her bloodstream was teeming with infection-fighting white cells, or leukocytes...
Houghton died Sunday from a wound that police said was self-inflicted. The suicide was the first at Harvard since...
James P. Houghton '94 died of a gunshot wound to the chest, according to county medical examiners who performed an autopsy yesterday...