Word: wynder
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Dates: during 1950-1959
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...Ernest L. Wynder and I have reproduced cancer experimentally in mice by using merely the tars from tobacco smoke. This shows conclusively that there is something in cigarette smoke which can produce cancer. This is no longer merely a possibility. Our experiments have proved it beyond any doubt...
First Correlation. Not until 1949 did an earnest young researcher, Ernest Wynder, then a medical student at Washington University under Surgeon Graham, supply statistical evidence: among 200 victims of lung cancer, 95.5% were men with long histories of cigarette smoking. Other researchers began to check their files on lung cancer patients and found the same thing. In Britain a massive study pointed even more sharply to the same conclusion (TIME, Dec. 22). In Denmark cancer experts who had once pooh-poohed the idea gathered more data and reversed themselves...
Working with Research Assistant Adele B. Croninger, Drs. Graham and Wynder obtained tar from a machine which "smokes" thousands of cigarettes, then painted the tar on the backs of mice. It produced scores of cancers. While these skin cancers are not identical with lung cancer in man, they are so similar that the researchers are confident that human lung tissue reacts the same...