Word: wynder
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...cigarettes have now taken over nearly a third of the U.S. cigarette output. Are the filters really any good? Scientists insist that, while they may have incidental benefits, present filters are relatively futile against dangerous tobacco tars. But the Sloan-Kettering Institute's noted cancer fighter, Dr. Ernest Wynder, believes that he can render smoking less harmful partly by making filters more effective, partly by chemically treating the tobacco leaf. It remains to be seen whether the tobacco industry will adopt these means and, if so, whether a smoke will then taste like a smoke or like a laboratory...
...relatively harmless-without waiting for the substance to be isolated. This reassurance came last week from the man who, since his student days, has been busy amassing proof that heavy, long-continued cigarette smoking is the main cause of the recent dramatic increase in lung cancer: Dr. Ernest L. Wynder, 34, of Manhattan's Sloan-Kettering Institute...
...smoke, had his own answer: it was caused by smoking. Dr. Graham, who smoked half a pack a day, was at first unconvinced by his ebullient colleague. World War II halted further studies of this problem, but in 1947 a second-year medical student named Ernest L. Wynder went to Graham and suggested a statistical study of lung cancer in relation to cigarette smoking...
...pack a day for at least 20 years, and only one was a nonsmoker; among noncancer patients, only 50% smoked so much, and 11% were nonsmokers. The evidence was highly suggestive, but it fell short of proof that there was anything in cigarette smoke to cause cancer. Graham and Wynder (now of Manhattan's Sloan-Kettering Institute) went to work again. With tar from machine-smoked cigarettes they produced cancers on the backs of mice. In 1951 Dr. Graham quit smoking. That same year he retired...
Last week Dr. Ernest L. Wynder of Manhattan's Sloan-Kettering Institute and the University of Toronto's Dr. George Wright told fellow experts in Atlantic City that they had separated the tar (by machine-smoking tons of cigarettes) into acid, alkaline and neutral portions. These were subdivided again until the researchers found the active cancer-causing fraction. It proved to be in the neutral portion. Isolated and applied to mice in the laboratory, it produced many cancers. Although it constitutes only 1½% of the tar, the dangerous material contains many different chemical compounds, including a number...