Word: yew
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Dates: during 1990-1999
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...concerto, The Five Sacred Trees. According to Williams' program notes on his piece, it was inspired by the writings of poet Robert Graves about the prayers that ancient Celtic tribes incanted before felling a tree. While each tree had its own prayer, Williams invokes five: the great oak, Tortan, yew, ash and the Dathi tree. The work was commissioned by the New York Philharmonic for bassoonist Judith LeClair. In this week-end's performance, the solo bassoon part was played by the BSO's principal bassoonist Richard Svoboda, who has been with the orchestra since 1989. Svoboda's moving performance...
...fashion. Cyclophosphamide, the compound that finally banished Dustin Fagan's cancer, belongs to a broad class of drugs that damage the DNA molecule by plastering it with sticky cross-links, thus triggering the suicide sequence. By contrast, the taxoids--including taxol, the compound isolated from the bark of the yew tree that was approved by the Food and Drug Administration as a weapon against ovarian cancer in 1992--cause the same suicidal result by deactivating a molecular machine that, just before cell division, separates the DNA in each chromosome into two separate strands. Still other drugs known as topoisomerase...
...alliances in the region. "Not a single friend and ally would join us in such a strategy," suggests a ranking Administration official. "We'd be all alone, and that would cause severe strains with Japan, South Korea, Australia and in Southeast Asia." Singapore Senior Minister Lee Kuan Yew, an astute analyst of the region, takes the point a step further: "The last thing Asia wants is containment. First, it will not succeed. Second, you will have absolutely no influence on how China and its attitudes develop: it will be hostile and xenophobic to the West, and that's no good...
...KUAN YEW Singapore strongman wins settlement from Int'l Herald Trib for implying he's...litigious...
...largely destitute. Half of Vietnamese children suffer from chronic malnutrition. The country's remarkably high literacy levels-among communism's proudest accomplishments-have begun to decline, as teenagers race off to find jobs instead of staying in school. On a recent visit, Singapore's Senior Minister Lee Kuan Yew, a Hanoi favorite, complained that investment projects are "being held to ransom" by officials looking for payoffs. Harvard economist Dwight Perkins describes Vietnam as being in the "Twilight Zone," somewhere between a Stalinist command economy and a Western-style market economy, with only a hazy notion of how to complete...