Word: zoloft
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...also caused serious side effects, including sluggishness, weight gain and occasionally death from overdose. The ground was ripe for a better pill, and it wasn't long before scientists produced a new, highly targeted class of antidepressants, led by Prozac, which hit the U.S. market in 1987, followed by Zoloft in 1991 and Paxil in 1992. Instead of blanketing a broad range of brain chemicals, the drugs - known as selective serotonin reuptake inhibitors (SSRIs) - zeroed in on one: serotonin, a critical compound that ferries signals between nerve cells. SSRIs provided relief for the same percentage of patients as their predecessors...
...first son was born, he choked on his vomit and needed emergency treatment. Her son recovered, but after the incident, Philo became preoccupied with his safety and felt severe anxiety about protecting him - a common symptom of PPD. "After a one-minute conversation with my doctor, he gave me Zoloft and said it would make me and my baby happy," she recalls. But Philo says she started having suicidal and homicidal thoughts, which got stronger when another doctor raised her dosage. Eventually, Philo says, she weaned herself off the drug, and her violent feelings disappeared. (Zoloft, like other antidepressant drugs...
Attorney Brian Oxman, who helped represent Jackson during the molestation trial, says dozens of drug vials, including Zoloft, Percocet, Vicodin and Demerol, were found at the time. Oxman told TIME: "Instead of pursuing the evidence which was staring them right in the face really - overprescription by doctors, overprescription by employees who were providing him with their drugs - instead of pursuing that which was an obvious, easily proved case they went after the molestation...
...tale behind the canisters is indeed deeply disturbing. They hold the remains of 5,121 people who languished in the psychiatric hospital in Salem, Oregon - many of them for their entire adult lives - for reasons that nowadays might require nothing more than a Zoloft prescription and some couch time. The patients' conditions listed in hospital records include "worries about sex" and "worries about money" - "things everyone walks around with today," Maisel says. When these patients died, their relatives either had no money for a burial or no interest in claiming the bodies...
...Trauma of War Before the advent of SSRIs - Lilly's Prozac was the first to be approved by the FDA, in 1987, followed by Zoloft from Pfizer, Paxil from GlaxoSmithKline, Celexa from Forest Pharmaceuticals and others - existing antidepressants had many disabling side effects. Impaired memory and judgment, dizziness, drowsiness and other complications made them ill suited for troops in combat. The newer drugs have fewer side effects and, unlike earlier drugs, are generally not addictive or toxic, even when taken in large quantities. They work by keeping neural connections bathed in a brain chemical known as serotonin. That amplifies serotonin...