Word: zoloft
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Dates: during 2000-2009
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...figuring out what to do has grown more confusing. One of the best tools for fighting depression is the so-called SSRI class of drugs, including Prozac, Paxil and Zoloft. But evidence has been mounting that these relatively safe medications might trigger suicidal thoughts in some kids. While there's no proof that the drugs have actually caused any suicides, British authorities pretty much banned everything but Prozac last December for children under 18. And in March, the FDA warned that anyone taking antidepressants, including Prozac, should be monitored for emotional agitation...
...kids enough to make many definitive statements." Part of the problem is that the brain chemistry of kids is different from adults'. Prozac works for both groups, but Paxil seems to work only for grownups. Kids, moreover, are amazingly responsive to placebos. While 70% of kids get better on Zoloft, for example, 60% improve on sugar pills...
...urged the manufacturers of 10 popular antidepressants to issue new, more stringent warning labels. The drugs named in the advisory are Prozac, Zoloft, Wellbutrin, Zyban, Paxil, Celexa, Effexor, Serzone, Luvox and Remeron. Together these pills racked up sales of about $12 billion worldwide in 2002. Some experts believe that it was their very popularity that concerned the FDA. Many doctors, the agency apparently fears, are giving out the pills too freely, without adequate monitoring...
...issue is coming to a head. By last December, the British Medicines and Healthcare Products Regulatory Agency, the equivalent of the FDA, had declared Celexa, Effexor, Lexapro, Luvox, Paxil and Zoloft (but not Prozac) too risky for kids under 18. Two weeks ago, a task force of the American College of Neuropsychopharmacology fired back, saying that despite the risk of potentially serious side effects, it's riskier to withhold the drugs...
Depression and physical pain often go hand in hand, and new research suggests why it's important to recognize and treat both. In a group of 573 patients taking Prozac, Paxil or Zoloft, 24% were still not responding to the antidepressants after three months of treatment. The drugs were most likely to fail those who were in pain at the onset of treatment; the worse the pain, the less the drugs worked. The odds of a poor response were twice as high for patients in moderate pain and three to four times as high for those in severe pain...